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tecovirimat will improve the level or influence of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Use Warning/Watch. Tecovirimat is a weak inhibitor of CYP2C8 and CYP2C19. Monitor for adverse outcomes if coadministered with delicate substrates of such enzymes.

enasidenib will enhance the level or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Check. Enasidenib (a weak CYP2C19 inhibitor) may well maximize systemic exposure of sensitive CYP2C19 substrates. Keep track of and modify dose of substrate as clinically indicated.

topiramate will decrease the extent or outcome of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.

Limit dosage and length if concomitantly applied; monitor closely for respiratory despair and sedation

BRIVIACT would not demand titration – which means that you may not should improve your dose around a number of weeks. See Getting BRIVIACT for entire info on having BRIVIACT.

Suicidal views or steps may be due to points in addition to medicines. When you've got suicidal views or actions, your Health care provider may possibly check for other brings about. Don't use VALTOCO for those who:

Contrary to some other medication, VALTOCO is made with quickly-acting Intravail® know-how. This aids loosen the Areas between the nasal cells for more rapidly absorption of diazepam into the body.

A second dose really should not be provided when there is problem about the individual’s breathing, they need to have assist with their breathing, website or have extreme drowsiness.

Controlling your partial-onset seizures could mean using one or more antiepileptic medicines. BRIVIACT is often a prescription drugs which might be applied to take care of partial-onset seizures in men and women 1 thirty day period of age and older.

VALTOCO is the only real prescription nasal spray made use of to immediately deal with episodes of Repeated seizures in Older people and youngsters six a long time and more mature. It’s distinctive from a day-to-day anti-seizure drugs—you use VALTOCO only when necessary.

Reserve concomitant prescribing of those medications in people for whom other remedy alternatives are inadequate. Limit dosages and durations to the minimum amount required. Watch carefully for signs of respiratory melancholy and sedation.

Seizures could be a A part of your life, but your lifetime is a lot greater than your problem. If you're lacking out on what matters since your seizures usually are not underneath Manage, you have got the right to be expecting additional from the treatment method.

VALTOCO may perhaps damage your unborn little one. Are breastfeeding or plan to breastfeed. VALTOCO passes into your breast milk and may hurt your baby. Talk to your Health care service provider about The easiest method to feed your little one if you utilize VALTOCO. Notify your healthcare service provider about all of the medicines you're taking, such as prescription and about-the-counter medicines, natural vitamins, and herbal nutritional supplements.

sage decreases effects of diazepam by pharmacodynamic antagonism. Insignificant/Significance Mysterious. Theoretical interaction; some species of sage may perhaps result in convulsions.